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Kazuaki Chayama Selected Research

Biomarkers (Surrogate Marker)

1/2022Molecular Signature Predictive of Long-Term Liver Fibrosis Progression to Inform Antifibrotic Drug Development.
1/2022Molecular signatures of long-term hepatocellular carcinoma risk in nonalcoholic fatty liver disease.
1/2022Plasma MicroRNAs as noninvasive diagnostic biomarkers in patients with Brugada syndrome.
1/2021Genomic analysis for the prediction of prognosis in small-bowel cancer.
4/2020Serum amyloid A is a better predictive biomarker of mucosal healing than C-reactive protein in ulcerative colitis in clinical remission.
3/2020Classification of primary liver cancer with immunosuppression mechanisms and correlation with genomic alterations.
2/2020Genomic Characterization of Non-Invasive Differentiated-Type Gastric Cancer in the Japanese Population.
1/2020Tumor Fibroblast Growth Factor Receptor 4 Level Predicts the Efficacy of Lenvatinib in Patients With Advanced Hepatocellular Carcinoma.
1/2020Circulating cytokines and angiogenic factors based signature associated with the relative dose intensity during treatment in patients with advanced hepatocellular carcinoma receiving lenvatinib.
1/2020Serum miR-379 expression is related to the development and progression of hypercholesterolemia in non-alcoholic fatty liver disease.
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Kazuaki Chayama Research Topics

Disease

172Infections
10/2022 - 02/2002
158Neoplasms (Cancer)
10/2021 - 01/2002
136Hepatocellular Carcinoma (Hepatoma)
06/2022 - 01/2002
85Chronic Hepatitis C
10/2022 - 01/2006
83Fibrosis (Cirrhosis)
10/2022 - 01/2003
50Liver Cirrhosis (Hepatic Cirrhosis)
01/2022 - 08/2003
43Non-alcoholic Fatty Liver Disease
01/2022 - 12/2008
40Neoplasm Metastasis (Metastasis)
01/2021 - 01/2002
39Chronic Hepatitis B
10/2022 - 01/2003
39Carcinoma (Carcinomatosis)
03/2019 - 11/2002
36Stomach Neoplasms (Stomach Cancer)
06/2020 - 05/2002
33Colorectal Neoplasms (Colorectal Cancer)
06/2021 - 01/2002
25Hemorrhage
05/2022 - 01/2008
25Hepatitis B
01/2022 - 08/2004
24Liver Diseases (Liver Disease)
10/2022 - 07/2009
23Hepatitis C
09/2020 - 06/2007
21Thrombosis (Thrombus)
10/2021 - 10/2007
21Inflammation (Inflammations)
06/2020 - 08/2003
20Carcinogenesis
08/2021 - 01/2002
18Hepatitis
01/2021 - 07/2006
16Gastritis
01/2019 - 02/2002
15Hypertension (High Blood Pressure)
04/2022 - 05/2002
14Lymphatic Metastasis
08/2019 - 01/2002
12Atherosclerosis
07/2019 - 05/2003
12Anemia
06/2017 - 10/2010
11Cardiovascular Diseases (Cardiovascular Disease)
10/2020 - 02/2002
10Type 2 Diabetes Mellitus (MODY)
04/2022 - 05/2012
10Esophageal and Gastric Varices (Esophageal Varices)
01/2021 - 01/2008
10Body Weight (Weight, Body)
09/2015 - 01/2002
9Insulin Resistance
03/2022 - 01/2013
9Disease Progression
12/2021 - 12/2007
9Colonic Neoplasms (Colon Cancer)
05/2021 - 07/2006
9Ulcer
01/2018 - 04/2006
8Liver Neoplasms (Liver Cancer)
10/2022 - 05/2009
8Pathologic Constriction (Stenosis)
10/2021 - 01/2006
8Portal Hypertension
08/2021 - 01/2008
8Fatty Liver
07/2021 - 02/2011
8Hepatic Encephalopathy
11/2020 - 03/2011
8Adenoma (Adenomas)
11/2020 - 10/2003
8Hypoxia (Hypoxemia)
11/2019 - 06/2003
8Hyperemia
01/2019 - 05/2002

Drug/Important Bio-Agent (IBA)

102InterferonsIBA
01/2021 - 01/2002
66Ribavirin (Virazole)FDA LinkGeneric
12/2020 - 01/2006
61Antiviral Agents (Antivirals)IBA
02/2022 - 01/2003
43Proteins (Proteins, Gene)FDA Link
10/2022 - 05/2002
33Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2003
30RNA (Ribonucleic Acid)IBA
12/2021 - 04/2003
30daclatasvirIBA
01/2020 - 03/2012
28DNA (Deoxyribonucleic Acid)IBA
11/2021 - 12/2003
25Pharmaceutical PreparationsIBA
01/2022 - 01/2003
25asunaprevirIBA
01/2020 - 03/2012
23Alanine Transaminase (SGPT)IBA
01/2021 - 08/2007
22Sorafenib (BAY 43-9006)FDA Link
05/2021 - 01/2012
22Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2021 - 01/2010
22Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2019 - 11/2002
20Glucose (Dextrose)FDA LinkGeneric
03/2022 - 03/2011
20AntigensIBA
01/2021 - 01/2004
19telaprevirIBA
02/2018 - 02/2011
17Messenger RNA (mRNA)IBA
01/2020 - 11/2002
15Hemoglobins (Hemoglobin)IBA
04/2022 - 07/2006
15lenvatinibIBA
04/2022 - 01/2019
15CytokinesIBA
12/2021 - 12/2004
14Capsules (Microcapsules)IBA
10/2021 - 06/2012
14Lamivudine (Epivir)FDA Link
05/2015 - 04/2004
13Hepatitis B Surface Antigens (HBsAg)FDA Link
08/2021 - 02/2008
12SofosbuvirIBA
10/2022 - 04/2015
11Cisplatin (Platino)FDA LinkGeneric
06/2022 - 09/2002
11glecaprevir and pibrentasvirIBA
01/2021 - 01/2018
11CholesterolIBA
01/2020 - 04/2002
11Pepsinogen A (Pepsinogen)IBA
09/2017 - 02/2002
11Triglycerides (Triacylglycerol)IBA
03/2016 - 11/2002
11Acetylcholine (Acetylcholine Chloride)FDA Link
01/2013 - 02/2002
10BilirubinIBA
05/2022 - 07/2006
10rho-Associated KinasesIBA
01/2019 - 05/2003
10Fluorouracil (Carac)FDA LinkGeneric
12/2018 - 09/2004
9NucleosidesIBA
01/2022 - 05/2007
9MicroRNAs (MicroRNA)IBA
01/2022 - 01/2012
9ParaffinIBA
01/2021 - 05/2003
9SteroidsIBA
01/2021 - 11/2007
9Insulin (Novolin)FDA Link
10/2020 - 04/2002
9Protease Inhibitors (Protease Inhibitor)IBA
04/2020 - 07/2010
9entecavirFDA Link
12/2018 - 12/2007
9InterleukinsIBA
01/2017 - 04/2003
9Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
05/2016 - 06/2006
8Biological ProductsIBA
06/2021 - 01/2006
8EnzymesIBA
02/2021 - 05/2007
8Collagen Type IV (Type IV Collagen)IBA
01/2021 - 02/2011
8Indicators and Reagents (Reagents)IBA
01/2021 - 01/2003
8HDL CholesterolIBA
01/2020 - 02/2010
8LDL CholesterolIBA
01/2020 - 04/2002
8NucleotidesIBA
10/2019 - 10/2013
8Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
01/2019 - 11/2003
8Transaminases (Aminotransferases)IBA
03/2014 - 01/2002
8GastrinsIBA
03/2013 - 02/2002

Therapy/Procedure

217Therapeutics
10/2022 - 01/2002
38Drug Therapy (Chemotherapy)
06/2022 - 01/2004
24Liver Transplantation
10/2022 - 03/2004
18Radiotherapy
10/2021 - 09/2003
13Hepatectomy
07/2020 - 01/2011
10Aftercare (After-Treatment)
03/2019 - 05/2007